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Kaposi’s sarcoma-associated herpesvirus processivity factor (PF-8) recruits cellular E3 ubiquitin ligase CHFR to promote PARP1 degradation and lytic replication

Woo-Chang Chung, Seungrae Lee, Yejin Kim, Jong Bok Seo, Moon Jung Song

Kaposi’s sarcoma-associated herpesvirus processivity factor (PF-8) recruits cellular E3 ubiquitin ligase CHFR to promote PARP1 degradation and lytic replication
Abstract Kaposis sarcomaassociated herpesvirus (KSHV), which belongs to the gammaherpesvirus subfamily, is associated with the pathogenesis of various tumors. Nuclear enzyme poly(ADP-ribose) polymer… Source : https://journals.plos.org/plosone/article?id=10.1371/journal.ppat.1009261